Recombinant von Willebrand factor and tranexamic acid for heavy menstrual bleeding in patients with mild and moderate von Willebrand disease in the USA (VWDMin): a phase 3, open-label, randomised, crossover trial
Margaret V. Ragni, Scott D. Rothenberger, Robert Feldman, Danielle Nance, Andrew D. Leavitt, Lynn Malec, Roshni Kulkarni, Robert F. Sidonio, Eric H. Kraut, Joseph L. Lasky, Rajiv K. Pruthi, Dana E. Angelini, Claire S. Philipp, Nina Hwang, Allison P. Wheeler, Craig D. Seaman, Nicoletta Machin, Frederico Xavier, Michael Meyer, Daniel B. Bellissimo, Gregory Humphreys, Kenneth J. Smith, Elizabeth P. Merricks, Timothy C. Nichols, Dana Ivanco, Deborah Vehec, Glory Koerbel, Andrew D. Althouse
Topics & Concepts
MedicineTranexamic acidVon Willebrand diseaseVon Willebrand factorOpen labelCrossover studyMenstrual bleedingClinical trialInternal medicineRecombinant DNASurgeryGastroenterologyGynecologyPlaceboBlood lossPlateletPathologyBiochemistryAlternative medicineChemistryGenePlatelet Disorders and TreatmentsHemophilia Treatment and ResearchBlood Coagulation and Thrombosis Mechanisms