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Metal-free iminyl radical-mediated C–C single bond cleavage/functionalization of redox-active oxime esters

Miaomiao Zhang, Shihong Li, Jia‐Lin Tu, Qingqiang Min, Feng Liu

2020Organic Chemistry Frontiers28 citationsDOI

Abstract

By photoactivating Hantzsch ester (HE) to act as an electron donor, we have achieved single-electron reduction of cycloketone oxime esters, thus providing a novel catalyst-free strategy for alkylation, allylation, vinylation and alkynylation.

Topics & Concepts

ChemistryOximeAlkynylationBond cleavageRedoxSurface modificationAlkylationCleavage (geology)CatalysisMetalCombinatorial chemistryOrganic chemistryEngineeringGeotechnical engineeringFracture (geology)Physical chemistryRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques
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