Indole-3-propionic acid function through PXR and AhR, molecular signaling pathways, and antitoxic role in underlying diseases
Cyrus Jalili, Foruzan Hosseinkhani, Dian Dayer, Mohammad Reza Tabandeh, Ardeshir Abbasi, Touraj Zamir Nasta
Topics & Concepts
Aryl hydrocarbon receptorPregnane X receptorDysbiosisReceptorFunction (biology)Proinflammatory cytokineBiologySignal transductionCell biologyOxidative stressBiochemistryGut floraMetabolic pathwayNeuroprotectionSecretionChemistryMetabolismGut–brain axisEffectorPharmacologyInflammationTransporterIntestinal epitheliumMetaboliteBiological pathwayGeneBarrier functionInducerIntestinal mucosaRegulation of gene expressionCell signalingGene expressionGastrointestinal functionPregnaneOrganic anion transporter 1Systemic circulationImmune systemOxidative phosphorylationHedgehog signaling pathwayBiological activityImmune cells in cancerNuclear Receptors and SignalingDrug Transport and Resistance Mechanisms