Crocetin ameliorates chronic restraint stress-induced depression-like behaviors in mice by regulating MEK/ERK pathways and gut microbiota
Susu Lin, Qiaoqiao Li, Shanshan Jiang, Zijin Xu, Yu Jiang, Ling Liu, Jinyan Jiang, Yingpeng Tong, Ping Wang
Topics & Concepts
CrocetinCREBPharmacologyMAPK/ERK pathwayEndocrinologyNeurotrophic factorsChronic stressGinsengTail suspension testAspartate transaminaseHippocampusInternal medicineBrain-derived neurotrophic factorChemistryMedicineKinaseBehavioural despair testBiochemistryAlkaline phosphataseAntidepressantPathologyCarotenoidReceptorTranscription factorEnzymeGeneAlternative medicineSaffron Plant Research StudiesMedicinal Plants and Bioactive CompoundsHops Chemistry and Applications