LincRNA-immunity landscape analysis identifies EPIC1 as a regulator of tumor immune evasion and immunotherapy resistance
Weiwei Guo, Yue Wang, Yue Wang, Min Yang, Zehua Wang, Yifei Wang, Yifei Wang, Smriti Chaurasia, Zhiyuan Wu, Min Zhang, Ghanshyam S. Yadav, Sanjay Rathod, Fernando Concha‐Benavente, Christian A. Fernandez, Song Li, Wen Xie, Robert L. Ferris, Udai S. Kammula, Binfeng Lu, Da Yang
Abstract
-EZH2 axis emerges as a potential mechanism for tumor immune evasion that can serve as therapeutic targets for immunotherapy.
Topics & Concepts
Evasion (ethics)ImmunotherapyRegulatorImmunityImmune systemImmunologyBiologyGeneGeneticsCancer Immunotherapy and BiomarkersCancer-related molecular mechanisms researchImmune Cell Function and Interaction