Synthesis and biological evaluation of some coumarin hybrids as selective carbonic anhydrase IX and XII inhibitors
Pavitra S. Thacker, Sridhar Goud Nerella, Omkar S. Argulwar, Jyothsna Soman, Andrea Angeli, Mallika Alvala, Mohammed Arifuddin, Claudiu T. Supuran
Topics & Concepts
ChemistryCoumarinCarbonic anhydraseStereochemistryPyrazoleLinkerGene isoformCombinatorial chemistryEnzymeBiochemistryOrganic chemistryComputer scienceGeneOperating systemEnzyme function and inhibitionSynthesis and Catalytic ReactionsChemical Reactions and Mechanisms