Interaction of Teleost Fish TRPV4 with DEAD Box RNA Helicase 1 Regulates Iridovirus Replication
Zhiyong Luo, Zhipeng Zhan, Xiao-Wei Qin, Weiqiang Pan, Mincong Liang, Chuanrui Li, Shaoping Weng, Jianguo He, Changjun Guo
Abstract
influx and interactions with DDX1 to collectively promote ISKNV replication, providing novel insights into the roles of the TRPV4-DDX1 axis in regulating the proviral effect of DDX1. This advances our understanding of viral disease outbreaks and would be of benefit for studies on preventing aquatic viral diseases.
Topics & Concepts
BiologyIridovirusRNA Helicase AFish <Actinopterygii>HelicaseReplication (statistics)Viral replicationCell biologyDEAD boxVirologyRNAGeneticsFisheryGeneVirusPlant Virus Research StudiesAnimal Virus Infections StudiesViral gastroenteritis research and epidemiology