Type I collagen proteolysis by matrix metalloproteinase-2 contributes to focal adhesion kinase activation and vascular smooth muscle cell proliferation in the aorta in early hypertension
Viviano Gomes de Oliveira Neves, Marcela M. Blascke de Mello, Daniel Rodrigues, Laena Pernomian, Isadora Sousa de Oliveira, Juliana Montenegro Parente, Eliane Candiani Arantes, Rita C. Tostes, Michele M. Castro
Topics & Concepts
Focal adhesionWestern blotMatrix metalloproteinaseVascular smooth muscleExtracellular matrixZymographyDoxycyclineRenovascular hypertensionCell growthChemistryInternal medicineEndocrinologyMedicineCellKidneyBiochemistrySmooth muscleAntibioticsGeneNitric Oxide and Endothelin EffectsProtease and Inhibitor MechanismsAortic aneurysm repair treatments