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Oxidative Three-Component Selenofunctionalization of Alkenes: Convenient Access to Vicinally Functionalized Selenides

Yun‐Qian Zhang, Yun-Qian Zhang, You‐Qin Jiang, Yong‐Hao Wang, Cong Qi, Yong Ling, Yanan Zhang, Yanan Zhang, Gong‐Qing Liu

2023The Journal of Organic Chemistry26 citationsDOI

Abstract

Three-component selenofunctionalization processes of olefins, diselenides and sulfonamides, water, alcohols, or acids utilizing 1-fluoropyridinium triflate (FP-OTf) as a reaction promoter are reported. Under the optimal conditions, a broad range of vicinally functionalized selenide derivatives was accessible with high yields and excellent functional group compatibilities. Mechanistic studies revealed that the FP-OTf played a key role in this selenofunctionalization process.

Topics & Concepts

SelenideTrifluoromethanesulfonateChemistryComponent (thermodynamics)Oxidative phosphorylationCombinatorial chemistryOrganic chemistryCatalysisSeleniumBiochemistryPhysicsThermodynamicsOrganoselenium and organotellurium chemistrySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods
Oxidative Three-Component Selenofunctionalization of Alkenes: Convenient Access to Vicinally Functionalized Selenides | Litcius