Click inspired synthesis of <i>p-tert</i>-butyl calix[4]arene tethered benzotriazolyl dendrimers and their evaluation as anti-bacterial and anti-biofilm agents
Anand K. Agrahari, Ashish K. Singh, Anoop Singh, Mala Singh, Pathik Maji, Shivangi Yadav, Sanchayita Rajkhowa, Pradyot Prakash, Vinod K. Tiwari
Abstract
CuAAC inspired calix-[4]arene tethered benzotriazolyl dendrimers were developed and investigated for their therapeutic potential, where <bold>7</bold> displayed potent anti-bacterial and anti-biofilm activities against drug-resistant & slime producing organisms.
Topics & Concepts
ChemistryDendrimerBiofilmCombinatorial chemistryCalixareneStereochemistryBacteriaOrganic chemistryMoleculeBiologyGeneticsClick Chemistry and ApplicationsDendrimers and Hyperbranched PolymersChemical Synthesis and Analysis