The combination of microbiome and metabolome to analyze the cross-cooperation mechanism of<i>Echinacea purpurea</i>polysaccharide with the gut microbiota<i>in vitro</i>and<i>in vivo</i>
Chang Liu, Wenhao Jiang, Fangwei Yang, Yuliang Cheng, Yahui Guo, Weirong Yao, Yong Zhao, He Qian
Abstract
, Lachnospiraceae), metabolites (tryptophan, beta-D-fructose 1,6-bisphosphate), and metabolism (glycosphingolipid biosynthesis), suggesting that they may be the key factors mediating the metabolic function of EPP. Therefore, EPP has the effect of enhancing the proliferation of gut-beneficial bacteria that metabolize polysaccharides and produce valuable metabolites.
Topics & Concepts
MetabolomeRuminococcusBiochemistryBiologyLachnospiraceaeGut floraBifidobacteriumMetabolismMicroecologyEubacteriumMicrobiologyLactobacillusFermentationMetaboliteFirmicutesBacteriaGenetics16S ribosomal RNAGeneHerbal Medicine Research StudiesGut microbiota and healthGinseng Biological Effects and Applications