CuCoFe Layered double hydroxides as laccase mimicking nanozymes for colorimetric detection of pheochromocytoma biomarkers
Fengwei Huang, Ke Ma, Xiu-Wen Ni, Sheng‐Lin Qiao, Kezheng Chen
Abstract
A laccase catalyzed colorimetric biosensing approach is promising for the detection of pheochromocytoma biomarkers, yet suffers from the poor stability of enzymes and high cost for production. Here we report for the first time an easy to produce, cheap, stable and reliable laccase-mimicking CuCoFe-LDHzyme, which can catalyze the oxidation of pheochromocytoma biomarkers to form a chromogenic product for smartphone-based colorimetric detection.
Topics & Concepts
LaccaseChromogenicChemistryPheochromocytomaCombinatorial chemistryBiosensorNanotechnologyEnzymeChromatographyBiochemistryMaterials scienceMedicineInternal medicineAdvanced Nanomaterials in CatalysisNanocluster Synthesis and ApplicationsAdvanced Photocatalysis Techniques