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Overexpression of long non-coding RNA AP001505.9 inhibits human hyaline chondrocyte dedifferentiation

Lin Chen, Jinying Xu, Shuang Lv, Yan Zhao, Dongjie Sun, Yangyang Zheng, Xianglan Li, Lihong Zhang, Guangfan Chi, Yulin Li

2021Aging10 citationsDOIOpen Access PDF

Abstract

experiments demonstrated that AP001505.9 overexpression inhibited dedifferentiation of chondrocytes. This study characterizes lncRNA expression profiles in human hyaline chondrocyte dedifferentiation, thereby identifying new potential mechanisms of chondrocyte dedifferentiation worthy of further investigation.

Topics & Concepts

ChondrocyteCell biologyRNAHyalineLong non-coding RNABiologyGeneGeneticsAnatomyCartilageBotanyCancer-related molecular mechanisms researchOsteoarthritis Treatment and MechanismsCircular RNAs in diseases