An enzyme nanopocket based on covalent organic frameworks for long-term starvation therapy and enhanced photodynamic therapy of cancer
Xiuyan Wan, Huiwen Zhang, Wei Pan, Na Li, Bo Tang
Abstract
An enzyme nanopocket constructed from a porphyrin-based covalent organic framework (COF) was developed to co-load glucose oxidase (GOx) and catalase (CAT) for long-term starvation therapy and enhanced photodynamic therapy (PDT).
Topics & Concepts
Photodynamic therapyCancer therapyCovalent bondCancerChemistryEnzymeTerm (time)Cancer researchBiochemistryMedicineInternal medicineOrganic chemistryPhysicsQuantum mechanicsNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisCarbon and Quantum Dots Applications