Covalent inhibition of ACSL4 alleviates ferroptosis-induced acute liver injury
Maoyuan Linghu, Xianyu Luo, Xinru Zhou, Didi Liu, Qian Huang, Yi Ru, Ying‐Li Luo, Yinchu Ma, Yi Huang
Topics & Concepts
CysteineCovalent bondLipid peroxidationChemistryBiochemistryProgrammed cell deathPotencyPharmacologyCancer researchEnzymeBiologyIn vitroApoptosisOrganic chemistryFerroptosis and cancer prognosisRNA modifications and cancerCancer, Lipids, and Metabolism