Cadmium disrupts mitochondrial distribution and activates excessive mitochondrial fission by elevating cytosolic calcium independent of MCU-mediated mitochondrial calcium uptake in its neurotoxicity
Ju Tang, Weixia Duan, Ping Deng, Huijuan Li, Cong Liu, Yu Duan, Min Feng, Shangcheng Xu
Topics & Concepts
NeurotoxicityMitochondrionMitochondrial fissionCell biologyBAPTACalciumUniporterMitochondrial ROSRuthenium redCytosolChemistryBiologyMitochondrial toxicityBiochemistryToxicityIntracellularEnzymeOrganic chemistryHeavy Metal Exposure and ToxicityTrace Elements in HealthAluminum toxicity and tolerance in plants and animals