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Extrathymic expression of Aire controls the induction of effective TH17 cell-mediated immune response to Candida albicans

Jan Dobeš, Osher Ben‐Nun, Amit Binyamin, Liat Stoler‐Barak, Bergithe E Oftedal, Yael Goldfarb, Noam Kadouri, Yael Gruper, Tal Givony, Itay Zalayat, Katarína Kováčová, Helena Böhmová, Evgeny Valter, Ziv Shulman, Dominik Filipp, Eystein S. Husebye, Jakub Abramson

2022Nature Immunology61 citationsDOI

Topics & Concepts

Candida albicansAutoimmune regulatorRAR-related orphan receptor gammaAutoimmunityImmunologyBiologyChronic mucocutaneous candidiasisImmune systemInnate lymphoid cellRegulatorCorpus albicansAcquired immune systemT cellMicrobiologyGeneFOXP3MedicineGeneticsDiseaseInternal medicineIL-33, ST2, and ILC PathwaysImmune Cell Function and InteractionAdrenal Hormones and Disorders
Extrathymic expression of Aire controls the induction of effective TH17 cell-mediated immune response to Candida albicans | Litcius