6-Methoxydihydrosanguinarine exhibits cytotoxicity and sensitizes TRAIL-induced apoptosis of hepatocellular carcinoma cells through ROS-mediated upregulation of DR5
Linlin Wang, Ruotong Li, Zi-heng Zang, Yun-xuan Song, Yuzhe Zhang, Tengfei Zhang, Feng-Ze Wang, Gangping Hao, Lu Cao
Topics & Concepts
ApoptosisDownregulation and upregulationChemistryViability assayCancer researchProtein kinase BCytotoxicityPoly ADP ribose polymeraseReactive oxygen speciesCell biologyBiologyBiochemistryIn vitroDNAGenePolymeraseCell death mechanisms and regulationBerberine and alkaloids researchMicroRNA in disease regulation