Litcius/Paper detail

Copper-catalysed homo-Mannich reaction of cyclopropanol for chiral piperidine synthesis

Yankun Zhao, Wenxuan Lin, Yulian Zhang, Guangcheng Pu, Zhuoyuan Jian, Hongya Yan, Ling He, Chengyang Wang, Qiuyuan Tan, Yu Lan, Min Zhang

2025Nature Catalysis8 citationsDOI

Topics & Concepts

Mannich reactionPiperidineChemistryStereoselectivityReaction conditionsCombinatorial chemistryCatalysisOrganic chemistryEnantioselective synthesisOrganic synthesisReaction mechanismMetalCopperStereoisomerismChemical synthesisCyclopropane Reaction MechanismsAsymmetric Hydrogenation and CatalysisAsymmetric Synthesis and Catalysis
Copper-catalysed homo-Mannich reaction of cyclopropanol for chiral piperidine synthesis | Litcius