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A facile green synthesis of 3,4-dihydropyrimidin-2(1H)-ones using cysteine as a bio-organic catalyst: Potent urease inhibitors, in vitro evaluation, kinetic mechanism, and molecular docking studies

Narges Hosseini Nasab, Hussain Raza, Rok Su Shim, Mubashir Hassan, Andrzej Kloczkowski, Song Ja Kim

2023Journal of Molecular Structure15 citationsDOI

Topics & Concepts

ChemistryUreaseThioureaCatalysisCysteineUreaEnzymeDocking (animal)Combinatorial chemistryPyrimidineViability assayIn vitroIC50StereochemistryBiochemistryOrganic chemistryNursingMedicineSynthesis and biological activityMulticomponent Synthesis of HeterocyclesMicrobial Applications in Construction Materials
A facile green synthesis of 3,4-dihydropyrimidin-2(1H)-ones using cysteine as a bio-organic catalyst: Potent urease inhibitors, in vitro evaluation, kinetic mechanism, and molecular docking studies | Litcius