Simultaneous Detection of a Cluster of Differentiation Markers on Leukemia-Derived Exosomes by Multiplex Immuno-Polymerase Chain Reaction via Capillary Electrophoresis Analysis
Netrapal Singh, Lin Huang, Dianbing Wang, Nan Shao, Xian‐En Zhang
Abstract
) levels of protein concentrations with high recovery (95%) in spiked serum sample experiments. We thus anticipate that the proposed method is promising in sensitive detection of multitargets to assist in the precise molecular typing of many complex diseases.
Topics & Concepts
ChemistryMyeloid leukemiaMultiplexCapillary electrophoresisDetection limitMolecular biologyMicrovesiclesFlow cytometryAnalytePolymerase chain reactionDNALeukemiaMultiplex polymerase chain reactionChromatographymicroRNACancer researchBiochemistryGeneBiologyImmunologyGeneticsExtracellular vesicles in diseaseAdvanced biosensing and bioanalysis techniquesNanopore and Nanochannel Transport Studies