Biomimetic cytomembrane nanovaccines prevent breast cancer development in the long term
Long Xiao, Yu Huang, Yuhe Yang, Zhiwei Miao, Jie Zhu, Mengdan Zhong, Chencheng Feng, Wenkai Tang, Jinhua Zhou, Lihong Wang, Xin Zhao, Zhirong Wang
Abstract
T cells and decreasing regulatory T cells in the tumor while increasing effector memory T cells in the spleen. Overall, our platform demonstrates that CCMP@R837 can be a potential candidate for preventive cancer vaccines in the clinic.
Topics & Concepts
Immune systemTerm (time)ImmunityBreast cancerCancerNanotechnologyImmune escapeBiologyChemistryMaterials sciencePhysicsImmunologyGeneticsQuantum mechanicsNanoplatforms for cancer theranosticsExtracellular vesicles in diseaseNanoparticle-Based Drug Delivery