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Encapsulation of doxorubicin in chitosan-alginate nanoparticles improves its stability and cytotoxicity in resistant lymphoma L5178 MDR cells

Krassimira Yoncheva, Borislav Tzankov, Yordan Yordanov, Ivanka Spassova, Daniela Kovacheva, Maria Frosini, Massimo Valoti, Virginia Tzankova

2020Journal of Drug Delivery Science and Technology35 citationsDOI

Topics & Concepts

DoxorubicinGlutathioneCytotoxicityChitosanPharmacologyDrug deliveryChemistryCytotoxic T cellAntioxidantMTT assayBiochemistryChemotherapyCell growthMedicineIn vitroOrganic chemistryInternal medicineEnzymeNanoparticle-Based Drug DeliveryChemotherapy-induced cardiotoxicity and mitigationChemotherapy-induced organ toxicity mitigation
Encapsulation of doxorubicin in chitosan-alginate nanoparticles improves its stability and cytotoxicity in resistant lymphoma L5178 MDR cells | Litcius