Association of skeletal muscle mass, kidney disease and mortality in older men and women: the cardiovascular health study
Nicholas T. Kruse, Petra Bůžková, Joshua I. Barzilay, Rodrigo J. Valderrábano, John A. Robbins, Howard A Fink, Diana Jalal
Abstract
/year decline in eGFR) in men, but was associated with lower risk of incident CKD in women ([adjusted RR=0.69, 95% (0.51,0.94)]. Low muscle mass (class II) was independently associated with higher mortality only in men [(adjusted HR=1.26, 95% (1.05,1.50)]. Neither definition of sarcopenia was associated with mortality in men or women with CKD. Further studies are needed to understand the mechanisms by which sarcopenia contributes to higher mortality in aging men.
Topics & Concepts
MedicineSkeletal muscleDiseaseCardiovascular healthMuscle massMuscle diseaseAssociation (psychology)GerontologyKidney diseaseInternal medicineSarcopeniaPhysiologyPsychologyPsychotherapistNutrition and Health in AgingBody Composition Measurement TechniquesNutritional Studies and Diet