Engineering a highly selective probe for ratiometric imaging of H<sub>2</sub>S<sub>n</sub> and revealing its signaling pathway in fatty liver disease
Wei Li, Lu Wang, Shulu Yin, Huanhua Lai, Lin Yuan, Xiaobing Zhang
Abstract
A highly selective probe (<bold>PPG-Np-RhPhCO</bold>) used for revealing the intracellular H<sub>2</sub>S<sub>n</sub> signaling pathways in a nonalcoholic fatty liver disease (NAFLD) model.
Topics & Concepts
Nonalcoholic fatty liver diseaseIntracellularFatty liverSignal transductionLiver diseaseDiseaseChemistryBiochemistryCell biologyComputational biologyMedicineBiologyPathologySulfur Compounds in BiologyMolecular Sensors and Ion DetectionEicosanoids and Hypertension Pharmacology