DMV biogenesis during β-coronavirus infection requires autophagy proteins VMP1 and TMEM41B
Ming-Ming Ji, Meng Li, Long Sun, Hongyu Deng, Yan Zhao
Abstract
KO cells, suggesting that appropriate PS levels also contribute to DMV formation. This work provides clues to the mechanism of how host proteins collaborate with viral proteins for endomembrane reshaping to promote viral infection.
Topics & Concepts
BiologyAutophagyBiogenesisCoronavirusVirologyCell biologyCoronavirus disease 2019 (COVID-19)GeneticsDiseaseApoptosisGeneMedicineInfectious disease (medical specialty)PathologyMosquito-borne diseases and controlAutophagy in Disease and TherapyVirus-based gene therapy research