Pd(<scp>ii</scp>)-Catalyzed atroposelective C–H olefination: synthesis of enantioenriched <i>N</i>-aryl peptoid atropisomers
Tianyu Jiang, Yi-Ting Ke, Yong‐Jie Wu, Qi‐Jun Yao, Bing‐Feng Shi
Abstract
The synthesis of N -aryl peptoid atropisomers via Pd( ii )-catalyzed atroposelective C–H olefination using commercially available l - p Glu-OH as the chiral ligand was reported.
Topics & Concepts
AtropisomerChemistryArylPeptoidLigand (biochemistry)StereochemistryCombinatorial chemistryOrganic chemistryPeptideAlkylBiochemistryReceptorAxial and Atropisomeric Chirality SynthesisMolecular spectroscopy and chiralityNonlinear Waves and Solitons