Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia
Nelly M. Cruz, Raghava Reddy, José L. McFaline‐Figueroa, Christine Tran, Hongxia Fu, Benjamin Freedman
Topics & Concepts
CiliumCiliopathyInduced pluripotent stem cellBiologyCell biologyCiliogenesisCiliopathiesPhenotypeMotile ciliumPolycystic kidney diseaseOrganoidHedgehogGeneticsSignal transductionEmbryonic stem cellGeneKidneyGenetic and Kidney Cyst DiseasesRenal and related cancersHedgehog Signaling Pathway Studies