Review of point-of-care platforms for diabetes: (1) sensing
Yiqun Liu, Xiaojin Luo, Qi Yu, Le Ye, Li Yang, Yue Cui
Abstract
Diabetes is a highly prevalent and chronic metabolic disease with a multifactorial etiology and various clinical manifestations. The point-of-care sensing platforms, as miniaturized devices being portable or worn on the body, are ideal approaches for monitoring diabetes, and can significantly improve the life qualities of diabetes patients with great convenience and comfort. In recent years, there have been many attempts for developing these miniaturized platforms. To successfully develop a point-of-care sensing platform for diabetes, there are several interesting questions: What are the mechanisms for sensing diabetes? How many biofluids are there for monitoring diabetes? Which type of biofluids could provide an accurate detection? What are the configurations of the sensing devices for each type of biofluid? Which is the current status for the development of the sensing devices? Which are the commercial devices for monitoring diabetes? This review will highlight our early attempts for addressing these questions. We believe this review could open up exciting opportunities for the development of the next-generation sensing devices for monitoring diabetes, as well as providing the diagnosis and monitoring methods for diabetes patients.