A Fast and Efficient Method for Detecting H<sub>2</sub>O<sub>2</sub> by a Dual-Locked Model Chemosensor
Jing Su, Shuping Zhang, Cairong Wang, Min Li, Jiajia Wang, Feng Su, Zhijun Wang
Abstract
A pentafluorobenzene-containing fluorescent probe GW-1 was designed and synthesized for monitoring hydrogen peroxide. The probe’s fluorescence was activated by a dual-locked model system that consists of a spiro location and a target analyte, which avoids the “alkalizing effect.” The smart GW-1 exhibited high selectivity toward hydrogen peroxide over other reactive oxygen species (ROS) by a dual-controlled molecular switch. These features are favorable for H2O2 sensing and pH changes in bioanalytical and biomedical applications.
Topics & Concepts
Hydrogen peroxideAnalyteFluorescenceReactive oxygen speciesBioanalysisSelectivityChemistryDual (grammatical number)Combinatorial chemistryOxygenPhotochemistryPeroxideNanotechnologyMaterials scienceCatalysisChromatographyOrganic chemistryBiochemistryArtLiteraturePhysicsQuantum mechanicsAnalytical Chemistry and SensorsMolecular Sensors and Ion DetectionElectrochemical sensors and biosensors