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Quercetin induces ferroptosis in gastric cancer cells by targeting SLC1A5 and regulating the p-Camk2/p-DRP1 and NRF2/GPX4 Axes

Lixian Ding, Shuwei Dang, Mingjun Sun, Dazhi Zhou, Yanyan Sun, Encheng Li, Shuqi Peng, Jinxing Li, Guodong Li, Jinxing Li, Guodong Li

2024Free Radical Biology and Medicine74 citationsDOI

Topics & Concepts

Programmed cell deathApoptosisDownregulation and upregulationChemistryIntracellularCell biologyCancer cellFlow cytometryGPX4AntioxidantQuercetinCancer researchBiochemistryBiologyMolecular biologyCancerSuperoxide dismutaseGeneGlutathione peroxidaseGeneticsFerroptosis and cancer prognosisCancer, Lipids, and MetabolismCancer-related molecular mechanisms research
Quercetin induces ferroptosis in gastric cancer cells by targeting SLC1A5 and regulating the p-Camk2/p-DRP1 and NRF2/GPX4 Axes | Litcius