In vivo target protein degradation induced by PROTACs based on E3 ligase DCAF15
Liang Li, Dazhao Mi, Haixiang Pei, Qiuhui Duan, Xinyue Wang, Wenbo Zhou, Jianping Jin, Dali Li, Mingyao Liu, Yihua Chen
Topics & Concepts
Ubiquitin ligaseProtein degradationIn vivoUbiquitinCell biologyComputational biologyDNA ligaseUbiquitin-Protein LigasesDegradation (telecommunications)ChemistryBiologyBiochemistryComputer scienceGeneticsDNATelecommunicationsGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis