Discovery of a non-covalent ligand for Rpn-13, a therapeutic target for hematological cancers
Cody A. Loy, Christine S. Muli, Eslam M.H. Ali, Dan Xie, Mostafa H. Ahmed, Carol Beth Post, Darci J. Trader
Topics & Concepts
ChemistryProteasomeCovalent bondCytotoxicityUbiquitinBiochemistryLigand (biochemistry)Cancer researchIn vitroReceptorBiologyOrganic chemistryGeneUbiquitin and proteasome pathwaysProtein Degradation and InhibitorsPeptidase Inhibition and Analysis