Mechanism of Polydiacetylene Blue-to-Red Transformation Induced by Antimicrobial Peptides
Johann Nuck, Kaori Sugihara
Abstract
Thermochromic temperature of polydiacetylene has been reported to coincide with the melting temperature of its lipidic monomers, indicating that the solid-to-liquid phase transition of monomers is linked to the color change. In this work, we study a hypothesis that peptide-induced chromism is similarly mediated by the lipid phase transition as many antimicrobial peptides are known to modulate the melting temperature of lipids.
Topics & Concepts
ThermochromismMonomerChemistryPeptideDiacetyleneAntimicrobialPhase transitionMelting temperatureAntimicrobial peptidesPhase (matter)Transformation (genetics)CrystallographyOrganic chemistryPolymerMaterials scienceBiochemistryThermodynamicsGeneComposite materialPhysicsPolydiacetylene-based materials and applicationsAntimicrobial Peptides and ActivitiesOcular Surface and Contact Lens