Spt20, a Structural Subunit of the SAGA Complex, Regulates Aspergillus fumigatus Biofilm Formation, Asexual Development, and Virulence
Yuan Chen, James I. P. Stewart, Shuai Liu, Donald C. Sheppard, Ling Lü, Shizhu Zhang
Abstract
Eukaryotic transcription is regulated by a large number of proteins, ranging from sequence-specific DNA-binding factors to transcriptional coactivators (chromatin regulators and the general transcription machinery) and their regulators. Previous research indicated that the sequence-specific complex SomA/PtaB regulates the biofilm formation and asexual development of Aspergillus fumigatus .
Topics & Concepts
ConidiationBiologyBiofilmAspergillus fumigatusVirulenceProtein subunitFungal proteinCell biologyMicrobiologyGeneSaccharomyces cerevisiaeGeneticsBacteriaAntifungal resistance and susceptibilityFungal and yeast genetics researchFungal Biology and Applications