Necrotic enteritis in chickens: a review of pathogenesis, immune responses and prevention, focusing on probiotics and vaccination
Mohammadali Alizadeh, Bahram Shojadoost, Nitish Boodhoo, Jake Astill, Khaled Taha-Abdelaziz, Douglas C. Hodgins, Raveendra R. Kulkarni, Shayan Sharif
Abstract
Necrotic enteritis (NE), caused by Clostridium perfringens (CP), is one of the most common of poultry diseases, causing huge economic losses to the poultry industry. This review provides an overview of the pathogenesis of NE in chickens and of the interaction of CP with the host immune system. The roles of management, nutrition, probiotics, and vaccination in reducing the incidence and severity of NE in poultry flocks are also discussed.
Topics & Concepts
Clostridium perfringensVaccinationImmune systemFlockImmunologyMedicineEnteritisIncidence (geometry)PathogenesisImmunityPathogenicityBiologyVirologyDiseaseHost (biology)NecrosisClostridium difficile and Clostridium perfringens researchVeterinary medicine and infectious diseasesAnimal Virus Infections Studies