Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy
Wentao Li, Shizhen Qiu, Jian Chen, Shutan Jiang, Wendong Chen, Jingwei Jiang, Fei Wang, Wen Si, Yilai Shu, Ping Wei, Gaofeng Fan, Ruijun Tian, Haitao Wu, Chenqi Xu, Haopeng Wang
Topics & Concepts
Chimeric antigen receptorDownregulation and upregulationUbiquitinAntigenEndosomeCell biologyBiologyIn vivoReceptorCancer researchImmunologyImmunotherapyBiochemistryImmune systemGeneticsGeneCAR-T cell therapy researchNanowire Synthesis and ApplicationsAdvancements in Semiconductor Devices and Circuit Design