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Synthesis and anti-tumor activity of nitrogen-containing derivatives of the natural product diphyllin

Yang Li, Qing Lu, Ruoxuan Xiao, Jing Ma, Yuqi Tang, Wantao Chen, Ruihan Zhang, Lingxi Jiang, Hao Chen, Baiyong Shen, Ao Zhang, Chunyong Ding

2022European Journal of Medicinal Chemistry25 citationsDOI

Topics & Concepts

ChemistryPancreatic cancerNatural productPotencyIC50AutophagyCell cycle checkpointAqueous solutionCell growthSolubilityCell culturePharmacologyLiver cancerCell cycleApoptosisCombinatorial chemistryBiochemistryCancer researchCancerIn vitroInternal medicineOrganic chemistryBiologyMedicineGeneticsAutophagy in Disease and TherapySynthesis of Indole DerivativesBioactive natural compounds
Synthesis and anti-tumor activity of nitrogen-containing derivatives of the natural product diphyllin | Litcius