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Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids

Wenxiang Hu, Chunjie Jiang, Mindy Kim, Wenjian Yang, Kun Zhu, Dongyin Guan, Wenjian Lv, Yang Xiao, Jessica R. Wilson, Daniel J. Rader, Ching‐Hon Pui, Mary V. Relling, Mitchell A. Lazar

2021Cell Metabolism32 citationsDOIOpen Access PDF

Topics & Concepts

BiologyEpigenomicsTranscriptomeChromatinInduced pluripotent stem cellGlucocorticoid receptorSingle-nucleotide polymorphismAdipose tissueGlucocorticoidGenome-wide association studyGeneticsGeneEndocrinologyGene expressionGenotypeEmbryonic stem cellDNA methylationImmune Cell Function and InteractionAdrenal Hormones and DisordersT-cell and B-cell Immunology
Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids | Litcius