Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685
Alshaima’a M. Qunies, Brittany D. Spitznagel, Yu Du, C. David Weaver, Kyle A. Emmitte
Topics & Concepts
ChemistrySodium channelPotassium channelhERGHEK 293 cellsIn vitroLead compoundPatch clampBiophysicsPharmacologyBiochemistryReceptorSodiumBiologyOrganic chemistryIon channel regulation and functionNeuroscience and Neuropharmacology ResearchEpilepsy research and treatment