Antibiotics increase aggression behavior and aggression-related pheromones and receptors in Drosophila melanogaster
Michal Grinberg, R. Levin, Hadar Neuman, O. Ziv, Sondra Turjeman, Gila Gamliel, Rita Nosenko, Omry Koren
Abstract
microbiota affects aggression as well as the pathways that underlie the behavior in this species. Male flies treated with antibiotics exhibited significantly more aggressive behaviors. Furthermore, they had higher levels of cVA and (Z)-9 Tricosene, pheromones associated with aggression in flies, as well as higher expression of the relevant pheromone receptors and transporters OR67d, OR83b, GR32a, and LUSH. These findings suggest that aggressive behavior is, at least in part, mediated by bacterial species in flies.
Topics & Concepts
AggressionDrosophila melanogasterSex pheromoneContext (archaeology)BiologyDrosophila (subgenus)Gut floraEcologyZoologyGeneticsPsychologyImmunologyGeneDevelopmental psychologyPaleontologyNeurobiology and Insect Physiology ResearchInsect and Pesticide ResearchInsect symbiosis and bacterial influences