M1 macrophages accelerate renal glomerular endothelial cell senescence through reactive oxygen species accumulation in streptozotocin-induced diabetic mice
Songyan Yu, Yu Cheng, Bing Li, Jing Xue, Yaqi Yin, Jieqing Gao, Zhengyuan Gong, Jie Wang, Yiming Mu
Topics & Concepts
SenescenceCell biologyMacrophageBiologyReactive oxygen speciesDownregulation and upregulationKidneyEndothelial stem cellStreptozotocinp38 mitogen-activated protein kinasesEndocrinologyInternal medicineMAPK/ERK pathwayDiabetes mellitusSignal transductionIn vitroMedicineBiochemistryGeneImmune cells in cancerTelomeres, Telomerase, and SenescenceAdvanced Glycation End Products research