Central composite optimization of ocular mucoadhesive cubosomes for enhanced bioavailability and controlled delivery of voriconazole
Mayada Said, Ahmed A. Aboelwafa, Ahmed Hassen Elshafeey, Ibrahim Elsayed
Topics & Concepts
ChitosanBioavailabilityPoloxamerCmaxMucoadhesionCentral composite designNanocarriersDrug deliveryMaterials scienceFactorial experimentParticle sizeChromatographyZeta potentialVoriconazoleChemistryPharmacologyDrug carrierNanotechnologyResponse surface methodologyComposite materialPolymerMathematicsMedicineNanoparticleAntifungalOrganic chemistryCopolymerPhysical chemistryDermatologyStatisticsAdvanced Drug Delivery SystemsOcular Surface and Contact LensLipid Membrane Structure and Behavior