Synthesis and characterization of polypyridine ruthenium(II) complexes and anticancer efficacy studies in vivo and in vitro
Lijuan Liang, Xiaoyun Wu, Chuanling Shi, Haoyu Wen, Shouhai Wu, Jing Chen, Chunxia Huang, Yi Wang, Yunjun Liu
Topics & Concepts
ChemistryApoptosisIn vitroIn vivoReactive oxygen speciesBromideRutheniumPoly ADP ribose polymeraseMitochondrionDownregulation and upregulationLigand (biochemistry)StereochemistryBiochemistryReceptorPolymeraseEnzymeBiologyCatalysisOrganic chemistryGeneBiotechnologyMetal complexes synthesis and propertiesCancer Mechanisms and TherapySynthesis of Tetrazole Derivatives