In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration
Yuemeng Jia, Lin Li, Yu-Hsuan Lin, Purva Gopal, Shunli Shen, Kejin Zhou, Xueliang Yu, Tripti Sharma, Yu Zhang, Daniel J. Siegwart, Joseph M. Ready, Hao Zhu
Topics & Concepts
BiologyCRISPRChromatinRegeneration (biology)DruggabilityCell biologyIn vivoComputational biologyLiver regenerationGeneticsDNAGeneCRISPR and Genetic EngineeringGenetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation