Electrochemical Organoselenium-Catalyzed Intermolecular Hydroazolylation of Alkenes with Low Catalyst Loadings
Zhoumei Tan, Xiang Fang, Kun Xu, Cheng‐Chu Zeng
Abstract
The organoselenium-catalyzed amination of alkenes is a promising way to construct functionalized amines. However, the use of chemical oxidants and the unavoidable formation of allylic amine or enamine are the two main limitations of these methodologies. Against this background, we herein report an electro-selenocatalytic regime for the hydroazolylation of alkenes with azoles under external oxidant-free conditions with low catalyst loadings. Moreover, this protocol enables the generation of amines without vinyl substituents.
Topics & Concepts
ChemistryCatalysisAllylic rearrangementAminationEnamineAmine gas treatingIntermolecular forceElectrochemistryCombinatorial chemistryOrganic chemistryMoleculePhysical chemistryElectrodeSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods