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Detection and Quantification of Chimeric Antigen Receptor Transgene Copy Number by Droplet Digital PCR versus Real-Time PCR

Yaoyao Lou, Caixia Chen, Xiaolu Long, Jia Gu, Min Xiao, Di Wang, Xiaoxi Zhou, Tongjuan Li, Zhenya Hong, Chunrui Li, Jianfeng Zhou, Liting Chen

2020Journal of Molecular Diagnostics54 citationsDOI

Topics & Concepts

RepeatabilityDigital polymerase chain reactionReproducibilityDetection limitReal-time polymerase chain reactionMolecular biologyChemistryChimeric antigen receptorPolymerase chain reactionBiologyImmunotherapyChromatographyImmunologyGeneBiochemistryImmune systemCAR-T cell therapy researchViral Infectious Diseases and Gene Expression in InsectsVirus-based gene therapy research
Detection and Quantification of Chimeric Antigen Receptor Transgene Copy Number by Droplet Digital PCR versus Real-Time PCR | Litcius