ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration
Jing-Yu Ding, Renjie Zhang, Huimin Li, Qiang Ji, Xiaomin Cheng, Rick F. Thorne, Hubert Hondermarck, Xiaoying Liu, Cailiang Shen
Abstract
system that can be used to evaluate other IVDD therapies.
Topics & Concepts
Intervertebral discCellular senescenceMesenchymal stem cellDegeneration (medical)SenescenceNucleusCell biologyNeuroscienceAnatomyBiologyMedicinePathologyPhenotypeBiochemistryGeneSpine and Intervertebral Disc PathologyPlant Toxicity and Pharmacological PropertiesPregnancy-related medical research