The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
Lisa Cucolo, Qingzhou Chen, Jingya Qiu, Yongjun Yu, Max Klapholz, Krista A. Budinich, Zhaojun Zhang, Yue Shao, Igor E. Brodsky, Martha S. Jordan, D. Gary Gilliland, Nancy R. Zhang, Junwei Shi, Andy J. Minn
Topics & Concepts
BiologyCancer researchRIPK1Immune checkpointCancer cellCancer immunotherapyInterferonTumor necrosis factor alphaCancerImmunotherapyImmune systemCell biologyImmunologyProgrammed cell deathNecroptosisApoptosisBiochemistryGeneticsImmune Cell Function and InteractionImmune cells in cancerinterferon and immune responses