Cov<sup>2</sup>MS: An Automated and Quantitative Matrix-Independent Assay for Mass Spectrometric Measurement of SARS-CoV-2 Nucleocapsid Protein
Bart Van Puyvelde, Katleen Van Uytfanghe, Laurence Van Oudenhove, Ralf Gabriels, Tessa Van Royen, Arne Matthys, Morteza Razavi, Richard Yip, Terry W. Pearson, Nicolas Drouin, Jan Claereboudt, Dominic Foley, R. Wardle, Kevin D. Wyndham, Thomas Hankemeier, Donald J. L. Jones, Xavier Saelens, Geert A. Martens, Christophe P. Stove, Dieter Deforce, Lennart Martens, Johannes P.C. Vissers, N. Leigh Anderson, Maarten Dhaenens
Abstract
MS assay can be adapted to test for many different pathogens in pooled samples, providing longitudinal epidemiological monitoring of large numbers of pathogens within a population as an early warning system.
Topics & Concepts
ChemistrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Mass spectrometryMatrix (chemical analysis)ChromatographyVirologyPathologyOutbreakMedicineInfectious disease (medical specialty)DiseaseBiologySARS-CoV-2 detection and testingBiosensors and Analytical DetectionAdvanced biosensing and bioanalysis techniques